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gyrB protein (Dialister invisus) - STRING interaction network
"gyrB" - DNA gyrase subunit B in Dialister invisus
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
gyrBDNA gyrase subunit B ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (649 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (815 aa)
  0.999
dnaN
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (369 aa)
 
  0.965
recF
DNA replication and repair protein RecF ; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (355 aa)
 
   
  0.883
GCWU000321_00644
RNA polymerase sigma factor SigA ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (394 aa)
   
 
  0.854
GCWU000321_00049
RNA polymerase sigma factor SigA ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (388 aa)
   
 
  0.854
dnaK
Heat shock protein 70 ; Acts as a chaperone (620 aa)
 
   
  0.835
dnaA
Chromosomal replication initiator protein DnaA ; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (541 aa)
   
   
  0.827
smc
Chromosome partition protein Smc ; Required for chromosome condensation and partitioning (1185 aa)
   
 
  0.806
rpoB
Transcriptase subunit beta ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1263 aa)
     
   
  0.771
dnaG
DNA primase ; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication (597 aa)
   
 
  0.768
Your Current Organism:
Dialister invisus
NCBI taxonomy Id: 592028
Other names: D. invisus, D. invisus DSM 15470, Dialister invisus, Dialister invisus DSM 15470, Dialister invisus Downes et al. 2003, Dialister invisus str. DSM 15470, Dialister invisus strain DSM 15470
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