STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDD_2016Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (558 aa)    
Predicted Functional Partners:
DDD_3159
Oxoisovalerate dehydrogenase alpha and beta fusion.
 
 0.999
DDD_3583
Pyruvate/2-oxoglutarate dehydrogenase.
 
 0.999
pdhA
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.998
DDD_2200
Putative pyruvate/2-oxoglutarate dehydrogenase, El component: transketolase.
 
 0.998
pdhB
Pyruvate 2-oxoglutarate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.993
lpd
Dihydrolipoyl dehydrogenase.
 0.993
lpdA2
Dihydrolipoyl dehydrogenase.
 0.992
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.964
DDD_0136
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.940
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.939
Your Current Organism:
Nonlabens dokdonensis
NCBI taxonomy Id: 592029
Other names: Donghaeana dokdonensis DSW-6, N. dokdonensis DSW-6, Nonlabens dokdonensis DSW-6, Nonlabens dokdonensis str. DSW-6, Nonlabens dokdonensis strain DSW-6, Persicivirga dokdonensis DSW-6
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