node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
deoB | pdxS | TGAM_0606 | TGAM_0629 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.800 |
deoB | pdxT | TGAM_0606 | TGAM_0630 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
deoB | pgm | TGAM_0606 | TGAM_0813 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Phosphoglucomutase (pgm). | 0.911 |
deoB | prs | TGAM_0606 | TGAM_2049 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Ribose-phosphate pyrophosphokinase (prs); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.937 |
deoB | rpiA | TGAM_0606 | TGAM_1781 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Ribose-5-phosphate isomerase (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.916 |
deoB | tk-1 | TGAM_0606 | TGAM_1599 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Transketolase C-terminal section (tk). | 0.901 |
deoB | tk-2 | TGAM_0606 | TGAM_1600 | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | Transketolase N-terminal section (tk). | 0.905 |
fdhA | pdxS | TGAM_0631 | TGAM_0629 | Formate dehydrogenase alpha subunit (fdhA); 2 probable transmembrane helices predicted by modhmm. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.510 |
fdhA | pdxT | TGAM_0631 | TGAM_0630 | Formate dehydrogenase alpha subunit (fdhA); 2 probable transmembrane helices predicted by modhmm. | Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.588 |
gap | pdxT | TGAM_1667 | TGAM_0630 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.465 |
gap | pgm | TGAM_1667 | TGAM_0813 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Phosphoglucomutase (pgm). | 0.425 |
gap | prs | TGAM_1667 | TGAM_2049 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Ribose-phosphate pyrophosphokinase (prs); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.492 |
gap | rpiA | TGAM_1667 | TGAM_1781 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Ribose-5-phosphate isomerase (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.415 |
gap | tk-1 | TGAM_1667 | TGAM_1599 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Transketolase C-terminal section (tk). | 0.852 |
gap | tk-2 | TGAM_1667 | TGAM_1600 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | Transketolase N-terminal section (tk). | 0.849 |
hisI | pdxT | TGAM_1613 | TGAM_0630 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family. | Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.464 |
hisI | prs | TGAM_1613 | TGAM_2049 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family. | Ribose-phosphate pyrophosphokinase (prs); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.765 |
pdxS | deoB | TGAM_0629 | TGAM_0606 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Phosphopentomutase (deoB); Belongs to the phosphohexose mutase family. | 0.800 |
pdxS | fdhA | TGAM_0629 | TGAM_0631 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Formate dehydrogenase alpha subunit (fdhA); 2 probable transmembrane helices predicted by modhmm. | 0.510 |
pdxS | pdxT | TGAM_0629 | TGAM_0630 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Glutamine amidotransferase subunit pdxT (pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |