close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (309 aa)    
Predicted Functional Partners:
TGAM_1240
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
   
 0.839
TGAM_1235
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
     0.803
TGAM_1238
Conserved hypothetical protein; 3 probable transmembrane helices predicted by modhmm.
       0.783
TGAM_1239
Hypothetical protein; 8 probable transmembrane helices predicted by modhmm.
       0.783
TGAM_1236
Conserved hypothetical protein; Belongs to DUF1641 family.
     
 0.782
cydA
Cytochrome bd ubiquinol oxidase, subunit I (cydA); 9 probable transmembrane helices predicted by modhmm.
 
   
 0.651
mbc2I
Membrane bound complex 2, subunit I (Mbc2I); 14 probable transmembrane helices predicted by modhmm.
     
 0.533
mbc2G
Membrane bound complex 2, subunit G (Mbc2G); 3 probable transmembrane helices predicted by modhmm.
       0.526
mbc2F
Membrane bound complex 2, subunit F (Mbc2F); 3 probable transmembrane helices predicted by modhmm.
       0.526
mbc2D
Membrane bound complex 2, subunit D (Mbc2D); 6 probable transmembrane helices predicted by modhmm.
       0.526
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (28%) [HD]