STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmB-1Peptidase T1A, 20S proteasome beta-subunit (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (201 aa)    
Predicted Functional Partners:
psmB-2
Peptidase T1A, 20S proteasome beta-subunit (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
  
 
0.904
TGAM_1720
RNA-metabolising metallo-beta-lactamase, beta-CASP family protein.
     
 0.830
psmA
Peptidase T1A, 20S proteasome alpha-subunit (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.794
TGAM_1719
Conserved hypothetical protein; 7 probable transmembrane helices predicted by modhmm.
       0.786
pan
ATP-dependent 26S proteasome regulatory subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP bindin [...]
  
 0.769
TGAM_0471
Metal-dependant protease, putative; Belongs to Mov34/MPN/PAD-1 family Contains Jab1/MPN domain.
   
 0.735
cdc48-2
AAA family ATPase, CDC48 subfamily (Cdc48).
  
 0.733
glpK-1
Glycerol kinase (glpK).
   
 0.612
glpK-2
Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.612
thsA-1
Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha subunit) (thsA); Belongs to the TCP-1 chaperonin family.
 
 
 0.518
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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