STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbcLRibulose 1,5-bisphosphate carboxylase large subunit (RuBisCO) (rbcL); Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (488 aa)    
Predicted Functional Partners:
gph
Hydrolase, HAD superfamily, Putative phosphoglycolate phosphatase (gph).
    
 0.916
TGAM_1181
Sucrose-phosphate phosphatase, putative, HAD-superfamily hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
  0.901
pulhA
Pullulan hydrolase type III (pulhA); 1 probable transmembrane helix predicted by modhmm.
     
 0.787
pycB
Pyruvate carboxylase subunit B (pycB).
       0.775
fucA
L-fuculose 1-phosphate aldolase (fucA).
  
  
 0.690
TGAM_0718
Carbonic anhydrase/acetyltransferase, containing bacterial transferase hexapeptide repeat.
   
 
 0.669
hps
3-hexulose-6-phosphate synthase-6-phospho 3-hexuloisomerase fused bifuntional enzyme (hps).
  
   
 0.627
fba
Fructose 1,6-bisphosphate aldolase class 1 (fba).
     
 0.607
eIF-2BI
Translation initiation factor eIF-2B subunit 1 (eIF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
  
 0.570
TGAM_1786
AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
   
 0.548
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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