node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TGAM_0032 | TGAM_1764 | TGAM_0032 | TGAM_1764 | Geranylgeranyl reductase. | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.601 |
TGAM_0032 | idsA | TGAM_0032 | TGAM_1828 | Geranylgeranyl reductase. | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Belongs to the FPP/GGPP synthase family. | 0.412 |
TGAM_0121 | TGAM_1764 | TGAM_0121 | TGAM_1764 | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.410 |
TGAM_0121 | fni | TGAM_0121 | TGAM_1826 | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | Isopentenyl-diphosphate delta-isomerase (fni); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.446 |
TGAM_1305 | TGAM_1764 | TGAM_1305 | TGAM_1764 | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.963 |
TGAM_1305 | carS | TGAM_1305 | TGAM_2129 | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.923 |
TGAM_1305 | idsA | TGAM_1305 | TGAM_1828 | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Belongs to the FPP/GGPP synthase family. | 0.456 |
TGAM_1763 | TGAM_1764 | TGAM_1763 | TGAM_1764 | Conserved hypothetical protein. | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.800 |
TGAM_1763 | TGAM_1765 | TGAM_1763 | TGAM_1765 | Conserved hypothetical protein. | GTP hydrolase, putative; Contains P-loop containing nucleoside triphosphate hydrolase, molybdopterin guanine dinucleotide synthesis protein B and cleavage/polyadenylation factor IA subunit clp1p motives. | 0.686 |
TGAM_1763 | TGAM_1766 | TGAM_1763 | TGAM_1766 | Conserved hypothetical protein. | Transcription regulator, asnC/Crp family. | 0.533 |
TGAM_1764 | TGAM_0032 | TGAM_1764 | TGAM_0032 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranyl reductase. | 0.601 |
TGAM_1764 | TGAM_0121 | TGAM_1764 | TGAM_0121 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | 0.410 |
TGAM_1764 | TGAM_1305 | TGAM_1764 | TGAM_1305 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.963 |
TGAM_1764 | TGAM_1763 | TGAM_1764 | TGAM_1763 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Conserved hypothetical protein. | 0.800 |
TGAM_1764 | TGAM_1765 | TGAM_1764 | TGAM_1765 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | GTP hydrolase, putative; Contains P-loop containing nucleoside triphosphate hydrolase, molybdopterin guanine dinucleotide synthesis protein B and cleavage/polyadenylation factor IA subunit clp1p motives. | 0.686 |
TGAM_1764 | TGAM_1766 | TGAM_1764 | TGAM_1766 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Transcription regulator, asnC/Crp family. | 0.533 |
TGAM_1764 | carS | TGAM_1764 | TGAM_2129 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.941 |
TGAM_1764 | fni | TGAM_1764 | TGAM_1826 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Isopentenyl-diphosphate delta-isomerase (fni); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.551 |
TGAM_1764 | gggPS | TGAM_1764 | TGAM_1175 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranylglyceryl phosphate synthase (GGGPS); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.969 |
TGAM_1764 | idsA | TGAM_1764 | TGAM_1828 | Prenyltransferase, UbiA family, Putative 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Belongs to the FPP/GGPP synthase family. | 0.703 |