node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FSU_0130 | apt | FSU_0130 | FSU_0263 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.943 |
FSU_0130 | guaA | FSU_0130 | FSU_0249 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | 0.884 |
FSU_0130 | guaB | FSU_0130 | FSU_3016 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.965 |
FSU_0130 | hpt | FSU_0130 | FSU_1170 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
FSU_0130 | purA | FSU_0130 | FSU_2115 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.982 |
FSU_0130 | surE | FSU_0130 | FSU_0779 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
FSU_0130 | xpt | FSU_0130 | FSU_2152 | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.456 |
FSU_3137 | apt | FSU_3137 | FSU_0263 | Cytidine/deoxycytidylate deaminase zinc-binding domain protein; Identified by match to protein family HMM PF00383. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.902 |
FSU_3137 | hpt | FSU_3137 | FSU_1170 | Cytidine/deoxycytidylate deaminase zinc-binding domain protein; Identified by match to protein family HMM PF00383. | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.904 |
FSU_3137 | xpt | FSU_3137 | FSU_2152 | Cytidine/deoxycytidylate deaminase zinc-binding domain protein; Identified by match to protein family HMM PF00383. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.969 |
apt | FSU_0130 | FSU_0263 | FSU_0130 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by similarity to SP:P15639; match to protein family HMM PF01808. | 0.943 |
apt | FSU_3137 | FSU_0263 | FSU_3137 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cytidine/deoxycytidylate deaminase zinc-binding domain protein; Identified by match to protein family HMM PF00383. | 0.902 |
apt | gmk | FSU_0263 | FSU_0818 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.950 |
apt | guaA | FSU_0263 | FSU_0249 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | 0.989 |
apt | guaB | FSU_0263 | FSU_3016 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.417 |
apt | hpt | FSU_0263 | FSU_1170 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.919 |
apt | surE | FSU_0263 | FSU_0779 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
apt | xpt | FSU_0263 | FSU_2152 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.900 |
gmk | apt | FSU_0818 | FSU_0263 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.950 |
gmk | guaA | FSU_0818 | FSU_0249 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888. | 0.964 |