node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APAF1 | CASP2 | ENSMLUP00000007636 | ENSMLUP00000013754 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 2; Belongs to the peptidase C14A family. | 0.965 |
APAF1 | CASP3 | ENSMLUP00000007636 | ENSMLUP00000002223 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.992 |
APAF1 | CASP8 | ENSMLUP00000007636 | ENSMLUP00000014156 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 8; Belongs to the peptidase C14A family. | 0.973 |
APAF1 | CASP9 | ENSMLUP00000007636 | ENSMLUP00000008827 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
APAF1 | ENSMLUP00000020832 | ENSMLUP00000007636 | ENSMLUP00000020832 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | annotation not available | 0.996 |
APAF1 | G1P2R3_MYOLU | ENSMLUP00000007636 | ENSMLUP00000004163 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Uncharacterized protein. | 0.983 |
APAF1 | LEO1 | ENSMLUP00000007636 | ENSMLUP00000003626 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | LEO1 homolog, Paf1/RNA polymerase II complex component. | 0.996 |
APAF1 | LOC102419640 | ENSMLUP00000007636 | ENSMLUP00000018972 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.996 |
APAF1 | LOC102420929 | ENSMLUP00000007636 | ENSMLUP00000018852 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.996 |
APAF1 | LOC102421025 | ENSMLUP00000007636 | ENSMLUP00000020649 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.996 |
CASP2 | APAF1 | ENSMLUP00000013754 | ENSMLUP00000007636 | Caspase 2; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.965 |
CASP2 | CASP3 | ENSMLUP00000013754 | ENSMLUP00000002223 | Caspase 2; Belongs to the peptidase C14A family. | Caspase 3; Belongs to the peptidase C14A family. | 0.837 |
CASP2 | CASP8 | ENSMLUP00000013754 | ENSMLUP00000014156 | Caspase 2; Belongs to the peptidase C14A family. | Caspase 8; Belongs to the peptidase C14A family. | 0.749 |
CASP2 | CASP9 | ENSMLUP00000013754 | ENSMLUP00000008827 | Caspase 2; Belongs to the peptidase C14A family. | Caspase 9; Belongs to the peptidase C14A family. | 0.805 |
CASP2 | ENSMLUP00000020832 | ENSMLUP00000013754 | ENSMLUP00000020832 | Caspase 2; Belongs to the peptidase C14A family. | annotation not available | 0.773 |
CASP2 | G1P2R3_MYOLU | ENSMLUP00000013754 | ENSMLUP00000004163 | Caspase 2; Belongs to the peptidase C14A family. | Uncharacterized protein. | 0.480 |
CASP2 | LOC102419640 | ENSMLUP00000013754 | ENSMLUP00000018972 | Caspase 2; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.773 |
CASP2 | LOC102420929 | ENSMLUP00000013754 | ENSMLUP00000018852 | Caspase 2; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.773 |
CASP2 | LOC102421025 | ENSMLUP00000013754 | ENSMLUP00000020649 | Caspase 2; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.773 |
CASP3 | APAF1 | ENSMLUP00000002223 | ENSMLUP00000007636 | Caspase 3; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.992 |