STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNGAP1Synaptic Ras GTPase activating protein 1. (1233 aa)    
Predicted Functional Partners:
KRAS
KRAS proto-oncogene, GTPase.
    
 0.925
NRAS
NRAS proto-oncogene, GTPase.
    
 0.925
RRAS2
RAS related 2.
    
 0.924
MRAS
Muscle RAS oncogene homolog.
    
 0.924
RRAS
RAS related.
    
 0.924
ARHGAP5
Rho GTPase activating protein 5.
    
 0.897
ARHGAP35
Rho GTPase activating protein 35.
    
 0.795
RASA3
RAS p21 protein activator 3.
    
0.772
ERAS
ES cell expressed Ras.
    
 0.763
DLG4
Discs large MAGUK scaffold protein 4.
   
 
 0.756
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.