node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tola_0974 | xseA | Tola_0974 | Tola_2173 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: asa:ASA_1036 RecJ single-stranded-DNA-specific exonuclease. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.515 |
Tola_0974 | xseB | Tola_0974 | Tola_2503 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: asa:ASA_1036 RecJ single-stranded-DNA-specific exonuclease. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.486 |
Tola_2380 | Tola_2504 | Tola_2380 | Tola_2504 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.923 |
Tola_2380 | hemC | Tola_2380 | Tola_3127 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.540 |
Tola_2380 | xseA | Tola_2380 | Tola_2173 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.439 |
Tola_2380 | xseB | Tola_2380 | Tola_2503 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.542 |
Tola_2504 | Tola_2380 | Tola_2504 | Tola_2380 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.923 |
Tola_2504 | dxs | Tola_2504 | Tola_2505 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.913 |
Tola_2504 | hemC | Tola_2504 | Tola_3127 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.450 |
Tola_2504 | thiI | Tola_2504 | Tola_2502 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.646 |
Tola_2504 | xseA | Tola_2504 | Tola_2173 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.610 |
Tola_2504 | xseB | Tola_2504 | Tola_2503 | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.898 |
coaD | xseB | Tola_0132 | Tola_2503 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.429 |
dxs | Tola_2504 | Tola_2505 | Tola_2504 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.913 |
dxs | thiI | Tola_2505 | Tola_2502 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.733 |
dxs | xseB | Tola_2505 | Tola_2503 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.836 |
hemC | Tola_2380 | Tola_3127 | Tola_2380 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: asa:ASA_3364 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.540 |
hemC | Tola_2504 | Tola_3127 | Tola_2504 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.450 |
hemC | xseB | Tola_3127 | Tola_2503 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.510 |
thiI | Tola_2504 | Tola_2502 | Tola_2504 | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | PFAM: Polyprenyl synthetase; KEGG: asa:ASA_0991 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.646 |