STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1224 aa)    
Predicted Functional Partners:
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.991
pheT
phenylalanyl-tRNA synthetase beta subunit; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.986
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
   
 0.983
leuS
leucyl-tRNA synthetase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.957
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.955
lysU
lysyl-tRNA synthetase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.951
glnS
glutaminyl-tRNA synthetase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770.
   
 0.943
asnS
asparaginyl-tRNA synthetase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770.
   
 0.935
ACU52752.1
Putative signal peptidase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770.
  
    0.862
valS
valyl-tRNA synthetase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770.
  
0.822
Your Current Organism:
Sulcia muelleri SMDSEM
NCBI taxonomy Id: 595499
Other names: C. Sulcia muelleri SMDSEM, Candidatus Sulcia muelleri SMDSEM, Candidiatus Sulcia muelleri str. SMDSEM, Candidiatus Sulcia muelleri strain SMDSEM
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