STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF126Ring finger protein 126. (309 aa)    
Predicted Functional Partners:
GET4
Golgi to ER traffic protein 4 homolog; As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of [...]
   
 
 0.755
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
 0.709
RSPO1
R-spondin 1.
   
 0.640
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.633
RSPO2
Uncharacterized protein.
   
 0.625
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
    
 0.553
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.553
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.538
LTN1
RING-CH-type domain-containing protein.
   
 0.532
RNF169
Ring finger protein 169.
    
 0.519
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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