node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NAMH_0109 | NAMH_0111 | NAMH_0109 | NAMH_0111 | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | 0.536 |
NAMH_0109 | NAMH_0114 | NAMH_0109 | NAMH_0114 | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | 0.517 |
NAMH_0109 | bioB | NAMH_0109 | NAMH_0112 | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.517 |
NAMH_0109 | topA | NAMH_0109 | NAMH_0110 | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.524 |
NAMH_0111 | NAMH_0109 | NAMH_0111 | NAMH_0109 | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | 0.536 |
NAMH_0111 | NAMH_0114 | NAMH_0111 | NAMH_0114 | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | 0.806 |
NAMH_0111 | bioB | NAMH_0111 | NAMH_0112 | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.803 |
NAMH_0111 | topA | NAMH_0111 | NAMH_0110 | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.808 |
NAMH_0114 | NAMH_0109 | NAMH_0114 | NAMH_0109 | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF02378. | 0.517 |
NAMH_0114 | NAMH_0111 | NAMH_0114 | NAMH_0111 | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | Phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | 0.806 |
NAMH_0114 | bioB | NAMH_0114 | NAMH_0112 | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.811 |
NAMH_0114 | topA | NAMH_0114 | NAMH_0110 | Sodium/hydrogen exchanger; Identified by match to protein family HMM PF00999. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.803 |
NAMH_0126 | NAMH_0314 | NAMH_0126 | NAMH_0314 | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 0.510 |
NAMH_0126 | bioA | NAMH_0126 | NAMH_0971 | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.997 |
NAMH_0126 | bioB | NAMH_0126 | NAMH_0112 | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.977 |
NAMH_0126 | bioD | NAMH_0126 | NAMH_1553 | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | Dethiobiotin synthase; Identified by match to protein family HMM TIGR00347. | 0.980 |
NAMH_0126 | topA | NAMH_0126 | NAMH_0110 | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.492 |
NAMH_0314 | NAMH_0126 | NAMH_0314 | NAMH_0126 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155. | 0.510 |
NAMH_0314 | bioA | NAMH_0314 | NAMH_0971 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.469 |
NAMH_0314 | bioB | NAMH_0314 | NAMH_0112 | biotin-[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.945 |