node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NAMH_0047 | guaA | NAMH_0047 | NAMH_0983 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.528 |
NAMH_0047 | panC | NAMH_0047 | NAMH_1383 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.660 |
NAMH_0622 | coaBC | NAMH_0622 | NAMH_1164 | Transcriptional activator, putative, Baf family; Identified by match to protein family HMM PF03309; match to protein family HMM TIGR00671. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.925 |
NAMH_0622 | panC | NAMH_0622 | NAMH_1383 | Transcriptional activator, putative, Baf family; Identified by match to protein family HMM PF03309; match to protein family HMM TIGR00671. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.965 |
NAMH_0622 | panD | NAMH_0622 | NAMH_1689 | Transcriptional activator, putative, Baf family; Identified by match to protein family HMM PF03309; match to protein family HMM TIGR00671. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.715 |
NAMH_1374 | NAMH_1381 | NAMH_1374 | NAMH_1381 | Type II and III secretion system protein; Identified by match to protein family HMM PF00263; Belongs to the bacterial secretin family. | Hypothetical protein; Identified by glimmer; putative. | 0.766 |
NAMH_1374 | panC | NAMH_1374 | NAMH_1383 | Type II and III secretion system protein; Identified by match to protein family HMM PF00263; Belongs to the bacterial secretin family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.557 |
NAMH_1374 | prfB | NAMH_1374 | NAMH_1382 | Type II and III secretion system protein; Identified by match to protein family HMM PF00263; Belongs to the bacterial secretin family. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.762 |
NAMH_1381 | NAMH_1374 | NAMH_1381 | NAMH_1374 | Hypothetical protein; Identified by glimmer; putative. | Type II and III secretion system protein; Identified by match to protein family HMM PF00263; Belongs to the bacterial secretin family. | 0.766 |
NAMH_1381 | panC | NAMH_1381 | NAMH_1383 | Hypothetical protein; Identified by glimmer; putative. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.558 |
NAMH_1381 | prfB | NAMH_1381 | NAMH_1382 | Hypothetical protein; Identified by glimmer; putative. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.773 |
coaBC | NAMH_0622 | NAMH_1164 | NAMH_0622 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, putative, Baf family; Identified by match to protein family HMM PF03309; match to protein family HMM TIGR00671. | 0.925 |
coaBC | panB | NAMH_1164 | NAMH_0682 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.539 |
coaBC | panC | NAMH_1164 | NAMH_1383 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.869 |
coaBC | panE | NAMH_1164 | NAMH_1158 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.511 |
guaA | NAMH_0047 | NAMH_0983 | NAMH_0047 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.528 |
guaA | panB | NAMH_0983 | NAMH_0682 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.560 |
guaA | panC | NAMH_0983 | NAMH_1383 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.557 |
panB | coaBC | NAMH_0682 | NAMH_1164 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.539 |
panB | guaA | NAMH_0682 | NAMH_0983 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.560 |