STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSIB_1041ATP-dependent RNA helicase, DEAD-family; Belongs to the DEAD box helicase family. (382 aa)    
Predicted Functional Partners:
TSIB_1842
Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.969
fusA
Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
 0.836
TSIB_1106
RNA-binding protein, containing KH domain.
   
 0.824
rpl3
50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.810
rps4
30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 0.803
TSIB_1678
RecJ-like exonuclease, containing OB-fold nucleic acid-binding domains.
  
 
 0.793
TSIB_1365
Predicted GTPase, containing NOG1 domain.
   
 
 0.790
TSIB_0798
NOP5/NOP56 related protein.
  
 
 0.784
rps6e
30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.773
rps9
30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
  
 0.770
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.