STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)    
Predicted Functional Partners:
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.986
RTN3
Reticulon.
   
 0.954
RTN4
Reticulon.
   
 0.946
APP
Amyloid beta precursor protein.
    
 0.915
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
  
  
 
0.901
PSEN1
Presenilin 1.
   
 
 0.772
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
     
 0.726
PSENEN
Presenilin enhancer, gamma-secretase subunit.
      
 0.687
NCSTN
Nicastrin.
    
 
 0.667
RTN2
Reticulon.
   
 
 0.666
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.