STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (334 aa)    
Predicted Functional Partners:
ccl
citryl-CoA lyase.
  
 0.995
fumA
Fumarate hydratase alpha subunit.
  
 
 0.992
fumB
Fumarate hydratase beta subunit.
  
 
 0.967
pycA
Pyruvate carboxylase large subunit.
    
 0.948
icd
Isocitrate dehydrogenase; Oxalosuccinate reductase.
  
 
 0.939
amnT1
Aminotransferase.
  
 0.921
acnA
Aconitate hydratase/aconitase.
  
 
 0.915
HTH_0035
Beta-lactamase-like protein.
  
  
 0.912
pycB
Pyruvate carboxylase small subunit.
   
 
 0.909
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.883
Your Current Organism:
Hydrogenobacter thermophilus
NCBI taxonomy Id: 608538
Other names: H. thermophilus TK-6, Hydrogenobacter thermophilus DSM 6534, Hydrogenobacter thermophilus TK-6, Hydrogenobacter thermophilus str. TK-6, Hydrogenobacter thermophilus strain TK-6
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