STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1WFQ4DNA_MISMATCH_REPAIR_2 domain-containing protein. (317 aa)    
Predicted Functional Partners:
A0A1Y1WI50
DNA mismatch repair protein MutL.
 
 0.951
A0A1Y1WC92
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.937
A0A1Y1WHE0
Uncharacterized protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
 
 0.929
A0A1Y1W995
MutL_C domain-containing protein.
 
 0.915
A0A1Y1WLW1
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.893
A0A1Y1WA49
PIN domain-like protein.
   
 0.887
A0A1Y1W5U7
Uncharacterized protein.
  
 0.875
A0A1Y1WA40
Uncharacterized protein.
  
 0.838
A0A1Y1W6D0
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.815
A0A1Y1VUK1
Vezatin domain-containing protein.
   
 0.800
Your Current Organism:
Linderina pennispora
NCBI taxonomy Id: 61395
Other names: ATCC 12442, CBS 312.51, L. pennispora, NRRL 2237
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.