STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A3Q0KD42Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1766 aa)    
Predicted Functional Partners:
A0A5K4ER40
Uncharacterized protein.
   
 0.988
A0A3Q0KPM9
Uncharacterized protein.
   
 0.987
CavBcon
Putative high voltage-activated calcium channel beta subunit 2.
   
 0.751
A0A3Q0KNF2
Putative high voltage-activated calcium channel beta subunit 2.
   
 0.751
A0A5K4EPB8
Putative high voltage-activated calcium channel beta subunit 2.
   
 0.751
A0A5K4EQE6
Putative high voltage-activated calcium channel beta subunit 2.
   
 0.751
A0A3Q0KMG2
Putative high voltage-activated calcium channel beta subunit 1.
   
 0.691
A0A3Q0KUF1
Putative wd-repeat protein.
   
 0.679
A0A3Q0KRP5
Uncharacterized protein.
    
 0.667
A0A3Q0KT99
UNC80 domain-containing protein.
   
 0.637
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.