STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5K4F138Uncharacterized protein. (374 aa)    
Predicted Functional Partners:
A0A3Q0KVD5
ATP-dependent Clp protease proteolytic subunit.
 
 0.976
A0A3Q0KNY0
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.724
A0A3Q0KL23
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
 
 
 0.642
A0A5K4ELM8
Lon protease homolog, mitochondrial.
 
 
 0.642
A0A3Q0KS05
Afg3-like protein 2 (M41 family).
 
 
  
 0.620
A0A3Q0KG66
AAA domain-containing protein; Belongs to the AAA ATPase family.
 
 
  
 0.570
A0A3Q0KPA4
Putative suppressor of potassium transport defect 3 (Skd3 protein).
  
 
 0.570
YME1_SCHMA
ATP-dependent zinc metalloprotease YME1 homolog; Putative ATP-dependent protease; In the N-terminal section; belongs to the AAA ATPase family.
 
 
  
 0.570
Smp_073500.2
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.549
A0A3Q0KBJ2
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
    
 
 0.543
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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