STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smp_101370.1Mesoderm induction early response 1 related. (727 aa)    
Predicted Functional Partners:
Smp_078280
Enoyl-CoA hydratase-related.
   
 
 0.676
A0A5K4EGN3
Enoyl-CoA hydratase-related.
   
 
 0.665
A0A5K4EHV1
Enoyl-CoA hydratase-related.
   
 
 0.665
A0A5K4FDQ2
Uncharacterized protein.
   
 
 0.584
Smp_039400
Eukaryotic translation initiation factor 5A.
      
 0.567
IF5A_SCHMA
Eukaryotic translation initiation factor 5A; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity).
      
 0.567
A0A3Q0KR93
Putative serine/threonine-protein kinase STE20.
   
 
 0.507
A0A5K4ETU0
Putative serine/threonine-protein kinase STE20.
    
 
 0.506
Smp_005210
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 
 0.495
PPIA_SCHMA
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
      
 0.491
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.