STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smp_049390Pyrroline-5-carboxylate reductase. (313 aa)    
Predicted Functional Partners:
A0A3Q0KNY0
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
 
 0.936
A0A3Q0KGZ5
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.935
Smp_068280
Putative prolyl 4-hydroxylase alpha subunit 1.
     
 0.900
A0A3Q0KL60
Putative cytochrome b5.
  
  
 0.721
A0A3Q0KBD1
Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.696
A0A3Q0KMZ1
Putative glutamyl-tRNA synthetase, cytoplasmic (Glutamate--tRNA ligase) (Glurs).
  
  
 0.591
A0A3Q0KH18
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
  
  
 0.541
Smp_038030
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.526
Smp_059980
Arginase.
   
  
 0.520
Smp_063830
GMP synthetase (Glutamine-hydrolysing).
     
 0.495
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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