STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mkk-4Protein CBR-MKK-4; Belongs to the protein kinase superfamily. (363 aa)    
Predicted Functional Partners:
jnk-1
Mitogen-activated protein kinase.
  
0.982
kgb-1
Mitogen-activated protein kinase.
  
0.981
mek-1
Protein CBR-MEK-1.
  
 
0.959
ced-2
Cell death abnormality protein 2; Required for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis. Also has a role in the migration of the 2 gonadal distal tip cells (DTCs) (By similarity). Belongs to the CRK family.
   
 
 0.930
arr-1
Protein CBR-ARR-1.
    
 0.929
fln-1
Protein CBG10542.
    
 0.906
CBG10541
Protein CBG10541.
    
 0.906
CBG14588
Protein CBG14588.
  
  
 
0.906
Cbr-fln-2.1
Protein CBR-FLN-2.1.
    
 0.906
CBG00447
Protein CBG00447.
  
0.822
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.