STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cbr-set-4Histone-lysine N-methyltransferase Suv4-20; Histone methyltransferase that specifically di- and trimethylates 'Lys-20' of histone H4 (H4K20me2/me3). H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Contributes to dosage compensation of X chromosome-relative to autosome-linked gene expression, possibly by converting H4K20me1 to H4K20m2/me3 on autosomes. Involved in the regulation of growth and body fat metabolism downstream of the TOR complex 2 pathway (326 aa)    
Predicted Functional Partners:
Cbr-set-1
annotation not available
   
  
 0.859
Cbr-set-18
annotation not available
   
  
 0.803
Cbr-lin-59
annotation not available
   
  
 0.750
Cbr-met-2
annotation not available
   
  
 0.748
CBG16281
annotation not available
   
  
 0.742
CBG03572
annotation not available
   
  
 0.725
Cbr-hsr-9
annotation not available
   
 
 0.711
Cbr-set-6
annotation not available
   
  
 0.675
Cbr-set-15
annotation not available
   
  
 0.657
let-268
annotation not available
     
  0.650
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae
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