STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ace-4Acetylcholinesterase 4; Rapidly hydrolyzes choline released into the synapse. (604 aa)    
Predicted Functional Partners:
ace-1
Acetylcholinesterase 1; Rapidly hydrolyzes choline released into the synapse; Belongs to the type-B carboxylesterase/lipase family.
  
  
0.916
ace-2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
0.912
gpcp-2
Protein CBG13338.
    
 0.906
CBG00479
Protein CBG00479.
     
  0.900
ckb-2.1
Protein CBR-CKB-2.
     
  0.900
ckb-4
Protein CBR-CKB-4.
     
  0.900
CBG10061
Protein CBG10061.
     
  0.900
cka-2
Protein CBR-CKA-2.
     
  0.900
ckb-2.2
Protein CBG18080.
     
  0.900
snb-1
Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function (By similarity).
     
 0.670
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.