STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpy-20Protein dumpy-20; Involved in cuticle function and is essential for normal morphological development. (439 aa)    
Predicted Functional Partners:
unc-24
Protein CBR-UNC-24.
      
 0.799
unc-119
Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system (By similarity). Belongs to the PDE6D/unc-119 family.
      
 0.797
rol-6
Protein CBR-ROL-6.
   
  
 0.796
myo-3
Myosin-3; Essential for muscle contraction. Involved in ovulation likely by regulating the contraction of gonadal myoepithelial sheath cells.
      
 0.721
unc-4
Protein CBR-UNC-4.
      
 0.626
bli-4
Protein CBR-BLI-4; Belongs to the peptidase S8 family.
      
 0.626
unc-22
Protein CBR-UNC-22.
      
 0.529
hlh-8
Protein CBR-HLH-8.
      
 0.512
lin-3
Protein CBR-LIN-3.
      
 0.502
dpy-18
Protein CBR-DPY-18.
      
 0.500
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.