src-2 protein (Caenorhabditis briggsae) - STRING interaction network

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Predicted Interactions

gene neighborhood

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[Homology]

Score

src-2

Tyrosine-protein kinase. (512 aa)

Predicted Functional Partners:

ssr-2

0.789

kin-32

0.782

sta-1

0.781

syg-2

0.745

lin-45

0.731

zig-10

0.710

sli-1

0.705

let-23

0.698

CBG12069

0.697

unc-89

0.697

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG12069	lin-45	A8XEH4	Q61UC4	Protein CBG12069.	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	0.601
CBG12069	src-2	A8XEH4	A8X798	Protein CBG12069.	Tyrosine-protein kinase.	0.697
CBG12069	ssr-2	A8XEH4	A8WRV4	Protein CBG12069.	Protein CBR-SSR-2.	0.829
CBG12069	syg-2	A8XEH4	A8X4J5	Protein CBG12069.	Protein CBR-SYG-2.	0.435
CBG12069	unc-89	A8XEH4	A8XEH5	Protein CBG12069.	Protein CBR-UNC-89.	0.479
kin-32	let-23	A8XBU1	A8WPC3	Protein CBR-KIN-32; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.736
kin-32	src-2	A8XBU1	A8X798	Protein CBR-KIN-32; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.782
let-23	kin-32	A8WPC3	A8XBU1	Receptor protein-tyrosine kinase.	Protein CBR-KIN-32; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.736
let-23	lin-45	A8WPC3	Q61UC4	Receptor protein-tyrosine kinase.	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	0.667
let-23	sli-1	A8WPC3	A8X5V5	Receptor protein-tyrosine kinase.	Protein CBR-SLI-1.	0.998
let-23	src-2	A8WPC3	A8X798	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.698
let-23	ssr-2	A8WPC3	A8WRV4	Receptor protein-tyrosine kinase.	Protein CBR-SSR-2.	0.516
let-23	sta-1	A8WPC3	Q61AP6	Receptor protein-tyrosine kinase.	Signal transducer and activator of transcription 1; Carries out a dual function: signal transduction and activation of transcription. Activated STAT proteins play a role in repression of dauer formation. Neuronal expression is held in check by negative signals through the TGF-beta pathway that target the daf-3 transcription factor (By similarity).	0.976
lin-45	CBG12069	Q61UC4	A8XEH4	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Protein CBG12069.	0.601
lin-45	let-23	Q61UC4	A8WPC3	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Receptor protein-tyrosine kinase.	0.667
lin-45	sli-1	Q61UC4	A8X5V5	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Protein CBR-SLI-1.	0.562
lin-45	src-2	Q61UC4	A8X798	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Tyrosine-protein kinase.	0.731
lin-45	ssr-2	Q61UC4	A8WRV4	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Protein CBR-SSR-2.	0.743
lin-45	sta-1	Q61UC4	Q61AP6	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Signal transducer and activator of transcription 1; Carries out a dual function: signal transduction and activation of transcription. Activated STAT proteins play a role in repression of dauer formation. Neuronal expression is held in check by negative signals through the TGF-beta pathway that target the daf-3 transcription factor (By similarity).	0.445
lin-45	unc-89	Q61UC4	A8XEH5	Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.	Protein CBR-UNC-89.	0.601