STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rho-1Protein CBR-RHO-1. (192 aa)    
Predicted Functional Partners:
let-502
Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization (By similarity).
   
 0.995
daam-1
Protein CBR-DAAM-1.
    
 0.990
act-5
Protein CBR-ACT-5.
   
 0.981
cyk-1
Protein CBR-CYK-1.
   
 0.977
ect-2
Protein CBR-ECT-2.
    
 0.960
rhi-1
Protein CBR-RHI-1.
   
 0.959
CBG12069
Protein CBG12069.
   
 0.948
unc-89
Protein CBR-UNC-89.
   
 0.948
let-363
Serine/threonine-protein kinase TOR.
    
 0.948
pkn-1
Protein CBR-PKN-1.
   
 0.948
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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