STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncr-2Protein CBR-NCR-2. (1222 aa)    
Predicted Functional Partners:
heh-1
Protein CBR-HEH-1.
   
 0.956
sbp-1
Protein CBR-SBP-1.
   
 0.875
daf-9
Protein CBR-DAF-9; Belongs to the cytochrome P450 family.
      
 0.727
daf-36
Protein CBR-DAF-36.
      
 0.697
dhs-16
Protein CBR-DHS-16.
   
  
 0.639
strm-1
Protein CBG15658; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
   
  
 0.587
daf-12
Protein CBR-DAF-12.
      
 0.534
cyn-9
Peptidyl-prolyl cis-trans isomerase 9; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imid ic peptide bonds in oligopeptides. Thought to function as a catalyst in the folding and modification of cuticle collagens (By similarity).
      
 0.472
emb-8
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
      
 0.449
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.