node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBG02060 | Cbr-tag-180 | A8WRW7 | A8WT73 | Protein CBG02060. | Protein CBR-TAG-180. | 0.906 |
CBG02060 | cca-1 | A8WRW7 | A8XPX1 | Protein CBG02060. | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | 0.619 |
CBG02060 | ccb-1 | A8WRW7 | A8XEA0 | Protein CBG02060. | Protein CBR-CCB-1. | 0.899 |
CBG02060 | ccb-2 | A8WRW7 | A8WWH4 | Protein CBG02060. | Protein CBR-CCB-2. | 0.662 |
CBG02060 | unc-36 | A8WRW7 | A8XP97 | Protein CBG02060. | Voltage-dependent calcium channel unc-36; May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response. Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects. May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement. Has a role in neural depolarization- induced calcium influx and pharyngeal pumping. Involved in restricting the expression of the putative olfactory receptor str-2 to only one of [...] | 0.924 |
CBG02060 | unc-43 | A8WRW7 | A8WXF6 | Protein CBG02060. | Calcium/calmodulin-dependent protein kinase type II; Role in locomotion and neuronal cell fate specification. Required for the regulation of synaptic density, egg laying, defecation, and meiotic maturation. Required for viability under chronic osmotic stress in which it acts downstream of osr-1. Regulates the synaptic trafficking of glr-1. Bidirectional modulator of neurotransmitter release with negative modulatory effects mainly mediated via slo-1 activation. May suppress the functional response to an internal pacemaker, perhaps by modulating the activity of the IP3 receptor (By simil [...] | 0.668 |
Cbr-tag-180 | CBG02060 | A8WT73 | A8WRW7 | Protein CBR-TAG-180. | Protein CBG02060. | 0.906 |
Cbr-tag-180 | cca-1 | A8WT73 | A8XPX1 | Protein CBR-TAG-180. | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | 0.778 |
Cbr-tag-180 | ccb-1 | A8WT73 | A8XEA0 | Protein CBR-TAG-180. | Protein CBR-CCB-1. | 0.987 |
Cbr-tag-180 | ccb-2 | A8WT73 | A8WWH4 | Protein CBR-TAG-180. | Protein CBR-CCB-2. | 0.971 |
Cbr-tag-180 | egl-19 | A8WT73 | A8X1H0 | Protein CBR-TAG-180. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.957 |
Cbr-tag-180 | nca-2 | A8WT73 | A8XS56 | Protein CBR-TAG-180. | Protein CBR-NCA-2. | 0.869 |
Cbr-tag-180 | unc-2 | A8WT73 | A8WRW6 | Protein CBR-TAG-180. | Protein CBR-UNC-2. | 0.955 |
Cbr-tag-180 | unc-36 | A8WT73 | A8XP97 | Protein CBR-TAG-180. | Voltage-dependent calcium channel unc-36; May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response. Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects. May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement. Has a role in neural depolarization- induced calcium influx and pharyngeal pumping. Involved in restricting the expression of the putative olfactory receptor str-2 to only one of [...] | 0.957 |
cca-1 | CBG02060 | A8XPX1 | A8WRW7 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Protein CBG02060. | 0.619 |
cca-1 | Cbr-tag-180 | A8XPX1 | A8WT73 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Protein CBR-TAG-180. | 0.778 |
cca-1 | ccb-1 | A8XPX1 | A8XEA0 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Protein CBR-CCB-1. | 0.769 |
cca-1 | ccb-2 | A8XPX1 | A8WWH4 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Protein CBR-CCB-2. | 0.769 |
cca-1 | egl-19 | A8XPX1 | A8X1H0 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.781 |
cca-1 | nca-2 | A8XPX1 | A8XS56 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] | Protein CBR-NCA-2. | 0.729 |