node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBG14703 | mec-12 | A8XKH6 | A8XXI7 | Protein CBG14703. | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.866 |
CBG14703 | mec-17 | A8XKH6 | A8XRF5 | Protein CBG14703. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | 0.632 |
CBG14703 | mec-18 | A8XKH6 | A8XJV8 | Protein CBG14703. | Protein CBR-MEC-18. | 0.803 |
CBG14703 | mec-3 | A8XKH6 | P34764 | Protein CBG14703. | Mechanosensory protein 3; Specifies differentiation of the set of six touch receptor neurons. Binds cooperatively as a heterodimer with unc-86 to sites in the mec-3 gene promoter. | 0.502 |
CBG14703 | mec-4 | A8XKH6 | Q17298 | Protein CBG14703. | Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. | 0.999 |
CBG14703 | mec-7 | A8XKH6 | Q17299 | Protein CBG14703. | Tubulin beta-1 chain; Tubulin is the major constituent of microtubules (Probable). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (Probable). Plays a role in mechanosensory transduction (touch sensitivity) (By similarity). | 0.774 |
coel-1 | mec-12 | A8XJV7 | A8XXI7 | Protein CBG14382. | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.640 |
coel-1 | mec-17 | A8XJV7 | A8XRF5 | Protein CBG14382. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | 0.632 |
hda-6 | mec-17 | A8XWT6 | A8XRF5 | Protein CBR-HDAC-6. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | 0.659 |
mec-12 | CBG14703 | A8XXI7 | A8XKH6 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Protein CBG14703. | 0.866 |
mec-12 | coel-1 | A8XXI7 | A8XJV7 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Protein CBG14382. | 0.640 |
mec-12 | mec-17 | A8XXI7 | A8XRF5 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | 0.868 |
mec-12 | mec-18 | A8XXI7 | A8XJV8 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Protein CBR-MEC-18. | 0.740 |
mec-12 | mec-3 | A8XXI7 | P34764 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Mechanosensory protein 3; Specifies differentiation of the set of six touch receptor neurons. Binds cooperatively as a heterodimer with unc-86 to sites in the mec-3 gene promoter. | 0.532 |
mec-12 | mec-4 | A8XXI7 | Q17298 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. | 0.742 |
mec-12 | mec-7 | A8XXI7 | Q17299 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Tubulin beta-1 chain; Tubulin is the major constituent of microtubules (Probable). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (Probable). Plays a role in mechanosensory transduction (touch sensitivity) (By similarity). | 0.789 |
mec-12 | ttll-5 | A8XXI7 | A8Y4E7 | Protein CBR-MEC-12; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Protein CBR-TTLL-5. | 0.521 |
mec-17 | CBG14703 | A8XRF5 | A8XKH6 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | Protein CBG14703. | 0.632 |
mec-17 | coel-1 | A8XRF5 | A8XJV7 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | Protein CBG14382. | 0.632 |
mec-17 | hda-6 | A8XRF5 | A8XWT6 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act [...] | Protein CBR-HDAC-6. | 0.659 |