STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBG18552Protein CBG18552. (515 aa)    
Predicted Functional Partners:
cya-1
Protein CBG06936; Belongs to the cyclin family.
   
 0.878
cdc-6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.865
cyb-3
Protein CBR-CYB-3; Belongs to the cyclin family.
   
 0.851
cyb-1
Protein CBR-CYB-1; Belongs to the cyclin family.
   
 0.851
npp-11
Protein CBR-NPP-11.
   
 0.849
fzr-1
Protein CBR-FZR-1.
   
 0.845
fzy-1
Protein CBR-FZY-1.
   
 0.845
cyd-1
Protein CBR-CYD-1; Belongs to the cyclin family.
   
 0.837
cye-1
G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...]
   
 0.827
CBG05210
Protein CBG05210; Belongs to the cyclin family.
   
 0.817
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.