STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dog-1Protein CBR-DOG-1. (885 aa)    
Predicted Functional Partners:
mus-101
Protein CBR-MUS-101.
   
 0.984
mlh-1
Protein CBR-MLH-1.
   
 0.972
pms-2
Protein CBR-PMS-2.
   
 0.948
brc-1
Protein CBR-BRC-1.
   
 0.913
him-6
Protein CBR-HIM-6.
  
 0.876
xpa-1
Protein CBR-XPA-1.
    
 0.873
xpf-1
Protein CBG03141.
   
 0.856
xpb-1
Protein CBG13269.
   
 0.843
gtf-2h2c
General transcription factor IIH subunit.
    
 0.840
CBG13719
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.839
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.