STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ari-2RBR-type E3 ubiquitin transferase. (415 aa)    
Predicted Functional Partners:
cul-5
Protein CBR-CUL-5; Belongs to the cullin family.
    
 
 0.947
rbx-2
Protein CBR-RBX-2.
    
 
 0.893
ned-8
Protein CBR-NED-8.
   
 0.856
CBG06964
Protein CBG06964.
      
 0.632
CBG13932
Protein CBG13932.
      
 0.632
cyld-1
Protein CBR-CYLD-1.
    
 0.605
ubc-24
Protein CBR-UBC-24.
   
 0.599
ubc-18
Protein CBR-UBC-18.
   
 0.599
ubl-1
Ubiquitin-like protein 1-40S ribosomal protein S27a; In the N-terminal section; belongs to the ubiquitin family.
   
 0.597
ikke-1
Protein CBR-IKKE-1.
    
 0.566
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.