STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyms-1Protein CBG20269. (315 aa)    
Predicted Functional Partners:
dhfr-1
Protein CBG12356; Belongs to the dihydrofolate reductase family.
 
 
 0.999
dut-1
Protein CBR-DUT-1.
  
 0.996
thk-1
Thymidine kinase.
  
 
 0.995
mel-32
Serine hydroxymethyltransferase; Interconversion of serine and glycine.
  
 
 0.994
CBG06863
Protein CBG06863.
  
 
 0.993
dao-3
Protein CBR-DAO-3.
  
 
 0.972
gcst-1
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
    
 0.962
CBG12961
Protein CBG12961.
    
 0.962
dtmk-1
Protein CBG01006.
  
 
 0.943
rnr-1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.933
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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