STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lis-1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (390 aa)    
Predicted Functional Partners:
nud-2
Protein CBR-NUD-2.
    
 
 0.966
nud-1
Protein CBR-NUD-1.
   
 0.962
dhc-1
Protein CBR-DHC-1.
   
 0.943
dyci-1
Protein CBR-DYCI-1.
   
 0.934
che-3
Protein CBR-CHE-3.
   
 0.927
CBG11861
Protein CBG11861.
   
 0.927
dnc-2
Protein CBR-DNC-2.
    
 0.926
dnc-1
Protein CBR-DNC-1.
    
 0.900
CBG22052
Protein CBG22052.
   
 0.804
dhc-3
Protein CBR-DHC-3.
    
 0.801
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.