STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpl-1Protein CBR-CPL-1; Belongs to the peptidase C1 family. (336 aa)    
Predicted Functional Partners:
CBG17499
Protein CBG17499; Belongs to the peptidase C1 family.
  
 0.967
asp-4
Protein CBR-ASP-4; Belongs to the peptidase A1 family.
   
 0.850
asp-3
Protein CBR-ASP-3; Belongs to the peptidase A1 family.
   
 0.845
CBG23516
Protein CBG23516.
   
 
 0.762
CBG22431
Protein CBG22431; Belongs to the peptidase C1 family.
   
 0.708
act-5
Protein CBR-ACT-5.
   
  
 0.655
crt-1
Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress- induced neurodegeneration (By similarity).
   
  
 0.636
cpi-2
Protein CBR-CPI-2.
      
 0.634
laat-1
Protein CBG07028.
      
 0.603
cpr-6
Protein CBR-CPR-6; Belongs to the peptidase C1 family.
  
0.595
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.