STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rga-9Rho-GAP domain-containing protein. (478 aa)    
Predicted Functional Partners:
rga-8
Rho-GAP domain-containing protein.
   
 
 0.950
spv-1
Spermathecal Physiology Variant.
   
 
 0.917
rga-4
Rho-GAP domain-containing protein.
     
 0.889
Y95B8A.12
Pleckstrin homology and RHoGef (RhoGEF) domain containing.
      
 0.813
chin-1
CHImaeriN (Rac-GTPase-activating protein) homolog.
     
 0.806
rhgf-1
RHo Guanine nucleotide exchange Factor.
      
 0.723
cgef-1
DH domain-containing protein.
      
 0.698
rho-1
Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...]
   
 0.691
rga-1
Rho-GAP domain-containing protein.
     
 0.635
rga-5
Rho-GAP domain-containing protein.
     
 0.628
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.