STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AC3.5Aminopeptidase-like protein AC3.5. (1090 aa)    
Predicted Functional Partners:
ltah-1.1
Aminopeptidase ltah-1.1; Aminopeptidase which preferentially removes N-terminal Arg and Lys residues from peptides and proteins.
  
 
 0.783
Y67D8C.9
Uncharacterized protein.
  
  
0.689
pept-1
Peptide transporter family 1; Low-affinity peptide transporter that is necessary for proton-dependent uptake of di- or tripeptides, and to a minor extent tetrapeptides, in the intestine. Transport is independent of sodium and chloride ions. Controls the uptake of dietary fatty acids, plays a role in fatty acid synthesis and is responsible for dipeptide-induced acidification of the intestine. Regulates cellular pH differences together with the antiporter protein, nhx-2. Amino acid uptake and absorption levels influence the insulin signaling/daf-2 and let-363/TOR pathways, subsequently a [...]
  
 
 0.647
anp-1
Aminopeptidase.
  
 
0.615
pam-1
Puromycin-sensitive aminopeptidase; Aminopeptidase. Required for the exit from meiosis, probably upstream of cyclin cyb-3. Involved in the establishment of the anterior-posterior polarity at the embryonic 1-cell stage by regulating the dynamics of sperm-donated centrosomes. Plays a role in oocyte maturation. Required for embryonic development. Belongs to the peptidase M1 family.
  
  
0.598
T16G12.1
Putative aminopeptidase-2; Putative aminopeptidase which plays a role in oocyte maturation.
  
 
 
0.571
Y42A5A.1
Aminopeptidase.
  
 
 
0.542
T12E12.6
Peptidase_M1 domain-containing protein.
  
  
 
0.534
F49B2.6
Aminopeptidase.
  
  
 
0.532
R03G8.6
Aminopeptidase.
  
  
 
0.521
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.