node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R05G6.5 | cat-4 | R05G6.5.1 | F32G8.6.1 | Uncharacterized protein. | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | 0.847 |
R05G6.5 | gcy-1 | R05G6.5.1 | AH6.1.1 | Uncharacterized protein. | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | 0.662 |
R05G6.5 | hap-1 | R05G6.5.1 | ZC395.7.1 | Uncharacterized protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.982 |
R05G6.5 | ndk-1 | R05G6.5.1 | F25H2.5.1 | Uncharacterized protein. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.909 |
R05G6.5 | ndx-4 | R05G6.5.1 | Y37H9A.6.1 | Uncharacterized protein. | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. | 0.910 |
R05G6.5 | pyk-1 | R05G6.5.1 | F25H5.3e.1 | Uncharacterized protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.914 |
cat-4 | R05G6.5 | F32G8.6.1 | R05G6.5.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Uncharacterized protein. | 0.847 |
cat-4 | gcy-1 | F32G8.6.1 | AH6.1.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | 0.800 |
cat-4 | hap-1 | F32G8.6.1 | ZC395.7.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.956 |
cat-4 | ndk-1 | F32G8.6.1 | F25H2.5.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.849 |
cat-4 | ndx-4 | F32G8.6.1 | Y37H9A.6.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. | 0.882 |
cat-4 | pyk-1 | F32G8.6.1 | F25H5.3e.1 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.818 |
gcy-1 | R05G6.5 | AH6.1.1 | R05G6.5.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Uncharacterized protein. | 0.662 |
gcy-1 | cat-4 | AH6.1.1 | F32G8.6.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | 0.800 |
gcy-1 | hap-1 | AH6.1.1 | ZC395.7.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
gcy-1 | ndk-1 | AH6.1.1 | F25H2.5.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.662 |
gcy-1 | ndx-4 | AH6.1.1 | Y37H9A.6.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. | 0.902 |
gcy-1 | pde-1 | AH6.1.1 | T04D3.3a.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Probable 3',5'-cyclic phosphodiesterase pde-1; Redundantly with pde-5, plays a role in the AFD thermosensory neurons to regulate microvilli receptive ending morphology, possibly by regulating cGMP levels. | 0.719 |
gcy-1 | pde-2 | AH6.1.1 | R08D7.6a.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Probable 3',5'-cyclic phosphodiesterase pde-2; May negatively regulate the activity of cGMP-dependent protein kinase egl-4 which in turn controls body size. | 0.787 |
gcy-1 | pde-3 | AH6.1.1 | E01F3.1i.1 | Receptor-type guanylate cyclase gcy-1; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of K+ gradient by the ASE right (ASER) sensory neuron. | Probable 3',5'-cyclic phosphodiesterase pde-3. | 0.724 |