STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sra-6Serpentine receptor class alpha-6. (329 aa)    
Predicted Functional Partners:
str-3
Seven TM Receptor.
   
  
 0.706
eat-4
Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior.
   
  
 0.667
str-1
Seven TM Receptor.
      
 0.661
str-2
Seven transmembrane receptor 2.
      
 0.660
srb-6
Serpentine receptor class beta-6; Mediates recognition and avoidance of Streptomyces species by detecting dodecanoic acid secreted by the bacteria. Also mediates avoidance of decanoic acid which is not secreted by Streptomyces species but this may represent an additional important avoidance response in the environment; Belongs to the nematode receptor-like protein srb family.
      
 0.568
kap-1
Kinesin-Associated Protein.
      
 0.550
osm-9
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.538
octr-1
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.535
unc-122
Olfactomedin-like domain-containing protein.
      
 0.531
odr-10
Serpentine receptor class r-10; An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway; Belongs to the nematode receptor-like protein str family.
   
  
 0.470
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.