STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sra-7Serpentine receptor class alpha-7. (329 aa)    
Predicted Functional Partners:
gcy-15
Receptor-type guanylate cyclase gcy-15; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
      
 0.800
srb-6
Serpentine receptor class beta-6; Mediates recognition and avoidance of Streptomyces species by detecting dodecanoic acid secreted by the bacteria. Also mediates avoidance of decanoic acid which is not secreted by Streptomyces species but this may represent an additional important avoidance response in the environment; Belongs to the nematode receptor-like protein srb family.
   
  
 0.703
str-1
Seven TM Receptor.
   
  
 0.548
gpa-4
Guanine nucleotide-binding protein alpha-4 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(i/o/t/z) subfamily.
      
 0.532
acr-5
Acetylcholine receptor subunit alpha-type acr-5; Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
      
 0.530
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.