Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cpg-1 | egg-3 | C07G2.1a.1 | F44F4.2.2 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | 0.735 |
| cpg-1 | mex-3 | C07G2.1a.1 | F53G12.5b.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Muscle EXcess. | 0.472 |
| cpg-1 | mex-5 | C07G2.1a.1 | W02A2.7.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Zinc finger protein mex-5; Functions with mex-6 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. Binds to mRNA in vitro, and inhibits pgl-3-mediated P-granule formation, probably by competing with pgl-3 for binding to mRNA. | 0.999 |
| cpg-1 | mex-6 | C07G2.1a.1 | AH6.5.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Zinc finger protein mex-6; Functions with mex-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. | 0.850 |
| cpg-1 | oma-2 | C07G2.1a.1 | ZC513.6.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.999 |
| cpg-1 | pie-1 | C07G2.1a.1 | Y49E10.14a.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Pharynx and intestine in excess protein 1; Maternally provided PIE-1 is required for germline cell fate determination. Functions as a repressor of RNA polymerase II-dependent gene expression in the developing germline. Required for expression of nos-2 in P4 germline blastomere cells. Inhibits the histone deacetylase activity of hda-1. Represses transcriptional activation of cdk-9 and cit-1.1, which are members of the P-TEFb complex. | 0.659 |
| cpg-1 | pos-1 | C07G2.1a.1 | F52E1.1.1 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | Cytoplasmic zinc-finger protein. | 0.999 |
| cpg-1 | spn-4 | C07G2.1a.1 | ZC404.8.2 | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | RRM domain-containing protein. | 0.598 |
| egg-3 | cpg-1 | F44F4.2.2 | C07G2.1a.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | 0.735 |
| egg-3 | mbk-2 | F44F4.2.2 | F49E11.1b.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2; Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis. Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos. Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage. | 0.982 |
| egg-3 | mex-3 | F44F4.2.2 | F53G12.5b.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Muscle EXcess. | 0.455 |
| egg-3 | mex-5 | F44F4.2.2 | W02A2.7.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Zinc finger protein mex-5; Functions with mex-6 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. Binds to mRNA in vitro, and inhibits pgl-3-mediated P-granule formation, probably by competing with pgl-3 for binding to mRNA. | 0.812 |
| egg-3 | mex-6 | F44F4.2.2 | AH6.5.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Zinc finger protein mex-6; Functions with mex-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. | 0.872 |
| egg-3 | oma-2 | F44F4.2.2 | ZC513.6.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.816 |
| egg-3 | pie-1 | F44F4.2.2 | Y49E10.14a.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Pharynx and intestine in excess protein 1; Maternally provided PIE-1 is required for germline cell fate determination. Functions as a repressor of RNA polymerase II-dependent gene expression in the developing germline. Required for expression of nos-2 in P4 germline blastomere cells. Inhibits the histone deacetylase activity of hda-1. Represses transcriptional activation of cdk-9 and cit-1.1, which are members of the P-TEFb complex. | 0.660 |
| egg-3 | pos-1 | F44F4.2.2 | F52E1.1.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Cytoplasmic zinc-finger protein. | 0.663 |
| egg-3 | spn-4 | F44F4.2.2 | ZC404.8.2 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | RRM domain-containing protein. | 0.550 |
| mbk-2 | egg-3 | F49E11.1b.1 | F44F4.2.2 | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2; Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis. Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos. Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage. | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | 0.982 |
| mbk-2 | mex-3 | F49E11.1b.1 | F53G12.5b.1 | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2; Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis. Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos. Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage. | Muscle EXcess. | 0.592 |
| mbk-2 | mex-5 | F49E11.1b.1 | W02A2.7.1 | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2; Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis. Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos. Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage. | Zinc finger protein mex-5; Functions with mex-6 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. Binds to mRNA in vitro, and inhibits pgl-3-mediated P-granule formation, probably by competing with pgl-3 for binding to mRNA. | 0.900 |
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