STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0001.7Uncharacterized protein. (735 aa)    
Predicted Functional Partners:
alg-5
Protein argonaute; Belongs to the argonaute family.
   
    0.540
inx-14
Innexin-14; Structural component of the gap junctions.
   
    0.537
cdc-25.1
M-phase inducer phosphatase cdc-25.1.
   
    0.537
F56F11.4
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
    0.524
gld-3
Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...]
   
    0.487
sun-1
Sun domain-containing protein 1; Involved in centrosome attachment to the nucleus. Required for zyg-12 localization to the nuclear envelope. Together with pot-1, it is required to anchor telomeres to the nuclear envelope in embryos.
   
    0.457
B0035.6
Enlarged Deps-1 Granule phenotype.
   
    0.451
pssy-2
PhosphatidylSerine SYnthase.
   
    0.450
F30F8.1
Uncharacterized protein.
   
    0.447
C08F8.3
Uncharacterized protein.
   
    0.445
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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