STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0034.5G_PROTEIN_RECEP_F1_2 domain-containing protein. (364 aa)    
Predicted Functional Partners:
dhs-17
DeHydrogenases, Short chain.
      
 0.882
C06A1.3
Putative serine/threonine-protein phosphatase C06A1.3.
      
 0.853
F14H8.2
Uncharacterized protein.
      
 0.850
F52E1.5
Uncharacterized protein.
      
 0.850
T22E5.6
Uncharacterized protein.
      
 0.810
twk-39
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.809
lgc-36
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.699
sdf-9
Protein sdf-9; Together with eak-4 and phosphatase eak-6, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1.
      
 0.690
asic-1
Degenerin-like protein asic-1; Proton-gated cation channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions (By similarity).
   
  
 0.661
nlp-15
Neuropeptide-Like Protein.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.