STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsp-20TetraSPanin family; Belongs to the tetraspanin (TM4SF) family. (279 aa)    
Predicted Functional Partners:
W05B5.1
Uncharacterized protein.
   
  
 0.898
T28D6.4
ANK_REP_REGION domain-containing protein.
   
  
 0.890
cex-2
Calexcitin-2.
   
  
 0.761
attf-2
AT hook Transcription Factor family.
      
 0.699
abhd-14
AB hydrolase-1 domain-containing protein.
   
  
 0.697
ZK899.1
Uncharacterized protein.
      
 0.692
bath-40
BTB and MATH domain-containing protein 40; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
      
 0.669
alx-1
Apoptosis-linked gene 2-interacting protein X 1; Required for lin-12 degradation after it has been internalised in the vulval precursor cells.
      
 0.660
nlp-15
Neuropeptide-Like Protein.
      
 0.504
Y54G2A.75
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
   
  
 0.422
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.