STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0280.17KH domain-containing protein. (260 aa)    
Predicted Functional Partners:
fubl-3
FUBp (FUBP) Like.
   
 
 0.851
bcc-1
SAM domain-containing protein.
      
 0.807
E02D9.1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.758
mxt-1
Eukaryotic translation initiation factor 4E-binding protein Mextli homolog; Plays a role in promoting translation.
      
 0.741
nhl-1
RING finger protein nhl-1.
    
 
 0.672
let-4
Leucine-rich repeat-containing protein let-4; Required for apical extracellular matrix organization and epithelial junction maintenance.
      
 0.660
acs-10
Fatty Acid CoA Synthetase family.
   
   0.627
vgln-1
ViGiLN homolog.
      
 0.610
hrpk-1
Heterogeneous nuclear ribonucleoprotein K homolog; RNA-binding protein which functions together with alg-1, a component of the miRNA loading complex, to modulate the processing and activity of specific miRNAs such as miR-58 and let-7 to regulate gene expression at the post-transcriptional level during embryonic, hypodermal and neuronal development. Promotes the lsy-6-mediated repression of cog-1 in uterine cells. In embryos, may play a role in the DNA damage response.
   
 
 0.610
gln-2
Probable glutamine synthetase.
   
  
 0.593
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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