node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0285.3 | B0495.8 | B0285.3.1 | B0495.8a.1 | Uncharacterized protein B0285.3. | Uncharacterized protein B0495.8; Belongs to the Luc7 family. | 0.403 |
B0285.3 | K10D2.5 | B0285.3.1 | K10D2.5.1 | Uncharacterized protein B0285.3. | Uncharacterized protein K10D2.5. | 0.400 |
B0285.3 | let-504 | B0285.3.1 | E01A2.4.2 | Uncharacterized protein B0285.3. | Nkap_C domain-containing protein. | 0.457 |
B0285.3 | mdt-18 | B0285.3.1 | C55B7.9a.3 | Uncharacterized protein B0285.3. | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.416 |
B0285.3 | smu-2 | B0285.3.1 | Y49F6B.4.1 | Uncharacterized protein B0285.3. | Smu-2 suppressor of mec-8 and unc-52 protein; Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-2 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17. In contrast, smu-2 mutants do not suppress the effects of an unc-52 mutation that affects the 5' splice site of exon 16. Required for normal accumulation of smu-1. Belongs to the RED family. | 0.529 |
B0285.3 | spt-4 | B0285.3.1 | F54C4.2.1 | Uncharacterized protein B0285.3. | Transcription elongation factor SPT4; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. | 0.414 |
B0285.3 | tipn-1 | B0285.3.1 | F23C8.9.1 | Uncharacterized protein B0285.3. | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. Belongs to the CSM3 family. | 0.502 |
B0285.3 | zgpa-1 | B0285.3.1 | C33H5.17.1 | Uncharacterized protein B0285.3. | Zinc finger G-PAtch domain-containing protein homolog. | 0.408 |
B0495.8 | B0285.3 | B0495.8a.1 | B0285.3.1 | Uncharacterized protein B0495.8; Belongs to the Luc7 family. | Uncharacterized protein B0285.3. | 0.403 |
B0495.8 | smu-2 | B0495.8a.1 | Y49F6B.4.1 | Uncharacterized protein B0495.8; Belongs to the Luc7 family. | Smu-2 suppressor of mec-8 and unc-52 protein; Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-2 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17. In contrast, smu-2 mutants do not suppress the effects of an unc-52 mutation that affects the 5' splice site of exon 16. Required for normal accumulation of smu-1. Belongs to the RED family. | 0.409 |
K10D2.5 | B0285.3 | K10D2.5.1 | B0285.3.1 | Uncharacterized protein K10D2.5. | Uncharacterized protein B0285.3. | 0.400 |
K10D2.5 | let-504 | K10D2.5.1 | E01A2.4.2 | Uncharacterized protein K10D2.5. | Nkap_C domain-containing protein. | 0.592 |
K10D2.5 | mdt-18 | K10D2.5.1 | C55B7.9a.3 | Uncharacterized protein K10D2.5. | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.846 |
K10D2.5 | smu-2 | K10D2.5.1 | Y49F6B.4.1 | Uncharacterized protein K10D2.5. | Smu-2 suppressor of mec-8 and unc-52 protein; Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-2 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17. In contrast, smu-2 mutants do not suppress the effects of an unc-52 mutation that affects the 5' splice site of exon 16. Required for normal accumulation of smu-1. Belongs to the RED family. | 0.551 |
K10D2.5 | tipn-1 | K10D2.5.1 | F23C8.9.1 | Uncharacterized protein K10D2.5. | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. Belongs to the CSM3 family. | 0.478 |
K10D2.5 | zgpa-1 | K10D2.5.1 | C33H5.17.1 | Uncharacterized protein K10D2.5. | Zinc finger G-PAtch domain-containing protein homolog. | 0.569 |
let-504 | B0285.3 | E01A2.4.2 | B0285.3.1 | Nkap_C domain-containing protein. | Uncharacterized protein B0285.3. | 0.457 |
let-504 | K10D2.5 | E01A2.4.2 | K10D2.5.1 | Nkap_C domain-containing protein. | Uncharacterized protein K10D2.5. | 0.592 |
let-504 | mdt-18 | E01A2.4.2 | C55B7.9a.3 | Nkap_C domain-containing protein. | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.697 |
let-504 | smu-2 | E01A2.4.2 | Y49F6B.4.1 | Nkap_C domain-containing protein. | Smu-2 suppressor of mec-8 and unc-52 protein; Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Selectively regulates alternative splicing of unc-52 exon 17. Thus, smu-2 mutants selectively suppress the effects of unc-52 nonsense mutations in exon 17 by promoting the accumulation of unc-52 isoforms that lack exon 17. In contrast, smu-2 mutants do not suppress the effects of an unc-52 mutation that affects the 5' splice site of exon 16. Required for normal accumulation of smu-1. Belongs to the RED family. | 0.600 |