STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0334.4PRELI/MSF1 domain-containing protein. (210 aa)    
Predicted Functional Partners:
mdmh-35
Uncharacterized protein mdmh-35; Belongs to the TRIAP1/MDM35 family.
   
 
 0.994
C02B8.6
Uncharacterized RING finger protein C02B8.6.
      
 0.852
srv-1
Serpentine receptor class V-1.
      
 0.852
Y48A6B.8
Uncharacterized protein.
      
 0.852
sri-19
Serpentine Receptor, class I.
      
 0.852
kdin-1
ANK_REP_REGION domain-containing protein.
      
 0.810
best-3
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
      
 0.806
Y71F9B.2
Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
   
 
 0.695
gsp-1
Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Dephosphorylates translation initiation factor eIF2alpha. Involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Belongs to the PPP phosphatase family. PP-1 subfamily.
   
  
 0.678
ugt-8
UDP-GlucuronosylTransferase.
      
 0.669
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.